David Bradley, Ph.D., Associate Professor
Project: Host Immune Responses
Mentor: David Bradley, Ph.D., Associate Professor
Location: Department of Biomedical Sciences, School of Medicine & Health Sciences
Description: The Bradley lab has several projects all focused on host immune responses running in parallel during the summer of 2022. The principle 2 projects would be: A) characterization of superantigens SEG and SEI as a cancer immunotherapy that stimulates the anti-tumor response. This project is completing the last pre-clinical studies with hopes of moving into the clinic in early fall; and B) investigation of macrophage associated phenotypes that are present in animals resistant to, compared to susceptible to, Yersinia pestis (the Plague). This study will ultimately be comparing M1 vs M2 macrophages in situ and ex vivo from dogs compared to humans, phenotypically by flowcytometry and functionally by ELISA.
