PATH 490.  Foundations of Translational Biomedical Research

Course Information:

Instructor:                          Scott Garrett, Ph.D.
Contact Info:            , 701.777.2657
Credit Hours:                      6
Meeting Times:                  8:30 am 4:30 pm M-F                                                  
Duration:                             Tuesday, May 28 Friday, Aug 2, 2019
Prerequisites:                     Biology (2 semesters)
Grading:                                Satisfactory / Unsatisfactory
Enrollment Max:                 21

Course Description:  The goal of translational biomedical research is to translate basic scientific findings in the laboratory setting into potential improvements in the prevention, diagnosis, and treatments for disease.  PATH 490 is a vital undergraduate research course that gives the opportunity for students to learn about and engage in translational biomedical research for credit during the summer.  Successful completion of this course may lead to an opportunity for the student to engage in independent research throughout the academic year.

Course Organization:  Students learn to conduct biomedical research by executing a small translational project, writing up the results and presenting it at the end of the summer in a simulated scientific meeting-poster session.  Students begin with basic training in laboratory techniques and safety before embarking on actual translational biomedical research experiments.   This is supplemented with many lectures on scientific concepts related to the research, most of which are either molecular biology or aspects of cancer and/or kidney disease.  Students are also exposed to other commonly utilized research techniques beyond their assigned research project through demonstrations.  Students will get exposure to state-of-the-art PCR, westerns, cell culture, flow cytometry, immunohistochemistry, and various microscopy techniques.

Students will receive peripheral lectures on a variety of diseases (autoimmune, cardiovascular, dementia, drug addiction, epilepsy, gastrointestinal, infectious/sepsis, and neuroimmunological) and topics (bioinformatics, epigenetics, public health and regenerative medicine).  The students will also learn about career opportunities and perspectives on various career pathways from School of Medicine faculty members, including MDs, MD/PhDs or program directors.  Students will receive tours of the new medical school building including the research labs, teaching facilities, anatomical labs, equipment cores, and patient SIM center.  The students will also receive presentations on the various post baccalaureate graduate and medical programs offered through the School of Medicine & Health Sciences (Biomedical Sciences, Clinical Translational Science, Medical Laboratory Science, Occupational Therapy, Physical Therapy, Physician Assistant, and Public Health).

Weekly seminars will deal with responsible conduct of research topics including research integrity/misconduct, conflicts of interest, data acquisition and management, authorship and publication, plagiarism, peer review, collaborative science, animal and human subject protections, and intellectual property.  Students will also attend seminars on animal care and use, biosafety and biosecurity, lab safety training and good laboratory practices, and scientists as members of society, as well as have workshops on scientific writing, how to write a research proposal, how to do literature searches, how to analyze data, and how to write an abstract and make a poster.  Overall, about two dozen faculty will be involved in some capacity with this course.  The PATH 490 course is an opportunity to experience what full-time research is like as well as an opportunity to learn more about the various medical fields.

Course Goals:  The overall goal of the course is to provide an opportunity for undergraduates to learn the necessary skills and techniques to be more successful in an independent laboratory biomedical research environment.

General Objectives:

1. To provide students the skills needed for independent, laboratory-based research.

2. To effectively manage time, effort and lab resources to match experimental and/or project objectives.

3. To critically evaluate and logically communicate experimental results.

Reimbursement / Completion fee:  Students will be reimbursed $3,000 upon successful completion of the course.

To Enroll

You must enroll in both sections (see below).  Send request to register through the Program Application. Direct any questions to Dr. Scott Garrett at or 701-777-2657.

Include application materials of current unofficial transcript and a one page narrative of academic goals, aspirations or other reasons you may have for taking this course.  Permission to register will be provide by the sending of two permission numbers via the e-mail given as contact.

Scott Garrett, Ph.D.
Associate Professor
Department of Pathology, W432
School of Medicine and Health Sciences
University of North Dakota
1301 N. Columbia Rd.
Grand Forks, ND 58202-9037
PATH 490-01
Directed Studies (Independent Study)
8:30AM - 4:30PM
May 28, 2019-
Jun 28, 2019
PATH 490-02
Directed Studies (Independent Study)
8:30AM - 4:30PM
Jul 1, 2019-
Aug 2, 2019
Building biomedical research capacity in North Dakota
by serving public universities and tribal colleges within the state
NDINBRE Supported By
Institutional Development Award (IDeA)
National Institute of General Medical Sciences
National Institutes of Health
North Dakota IDeA Network of Biomedical Research Excellence
University of North Dakota - School of Medicine & Health Sciences
1301 N. Columbia Road, Stop 9037 - Grand Forks, ND 58202-9037
Telephone: (701) 777-6376 - Fax: (701) 777-6372
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