RESEARCH EXPERIENCES FOR UNDERGRADUATES FROM RURAL AND TRIBAL COLLEGES
Investigator: Keith Henry, Ph.D.
Location: Department of Biomedical Sciences, University of North Dakota
Project Title: Identification of epigenetic changed induced by exposure to antidepressants
Description: The project will focus on identification of epigenetic changes that occur after exposure to antidepressants. Numerous animal studies now show that antidepressant exposure in early life leads to long-lasting behavior effects. Our primary goal is to identify the molecular and epigenetic changes such as DNA methylation and histone modifications that underlie this reprogramming. We utilize modern next-generation sequencing technologies and advanced molecular techniques.